c-met-IN-1CS-01Y69647_上海莼试生物技术有限公司

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一、概述：

化学性质：

规格	100mg 250mg 500mg
CAS	2084836-84-8
别名	N/A
化学名	N/A
分子式	C35H37FN6O5
分子量	640.7
溶解度	Soluble in DMSO
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

产品描述：

c-met-IN-1 (compound 16) is a potent and selective c-Met inhibitor, with IC50 of 1.1 nM, with antitumor activity.[1]. IC50: 1.1 nM (c-Met)[1]

c-met-IN-1 (compound 16) exhibits high selectivity and remarkable cytotoxicity against HT-29, MKN-45 and A549 cells with IC50 values of 0.08 μM, 0.22 μM and 0.07 μM, respectively[1].

[1]. Wang X, et al. Design, synthesis and biological evaluation of novel 4-(2-fluorophenoxy)quinoline derivatives as selective c-Met inhibitors. Bioorg Med Chem. 2017 Feb 1;25(3):886-896.

特别提醒：

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2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。

标签：c-met-IN-1

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