Rp-8-bromo-Cyclic AMPS (sodium salt)CS-01Y69398_上海莼试生物技术有限公司

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一、概述：

化学性质：

规格	500μg 1mg 5mg
CAS	925456-59-3
别名	N/A
化学名	N/A
分子式	C10H10BrN5O5PS •Na
分子量	446.1
溶解度	DMF: 30 mg/ml,DMSO: 25 mg/ml,Ethanol: 0.5 mg/ml,PBS (pH 7.2): 10 mg/ml
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

产品描述：

Rp-8-bromo-Cyclic AMPS (Rp-8-bromo-cAMPS) is a cell-permeable cAMP analog that combines an exocyclic sulfur substitution in the equatorial position of the cyclophosphate ring with a bromine substitution in the adenine base of cAMP. It acts as an antagonist of cAMP-dependent protein kinases (PKAs) and is resistant to hydrolysis by cyclic nucleotide phosphodiesterases. Rp-8-bromo-cAMPS more effectively antagonizes cAMP-dependent activation of purified PKA type I from rabbit muscle than PKA type II from bovine heart.

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标签：Rp-8-bromo-Cyclic AMPS (sodium salt)

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