化学性质:
规格 | 10mg 50mg |
CAS | 41179-33-3 |
别名 |
|
化学名 | 4-(2'-fluoro-[1,1'-biphenyl]-4-yl)-N-(4-hydroxyphenyl)butanamide |
分子式 | C22H20FNO2 |
分子量 | 349.4 |
溶解度 | <34.94mg/ml in DMSO; <34.94mg/ml in ethanol |
储存条件 | Store at RT |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
CMPD1 is a selective and non-ATP-competitive p38 MAPK-mediated MK2 phosphorylation inhibitor with apparent Ki (Kiapp) of 330?nM[1][2].
CMPD1 does not inhibit p38 MAPK-mediated phosphorylation of other two substrates, MBP and ATF2[1].CMPD1 induced mitotic arrest and apoptosis in U87 cells[1].CMPD1 inhibits tubulin polymerisation in glioblastoma cells[3].
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标签:CMPD-1
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