化学性质:
规格 | 500 μg 1 mg 5 mg |
CAS | 2410279-93-3 |
别名 | N/A |
化学名 | N/A |
分子式 | C26H40D4NO7S.Na |
分子量 | 541.7 |
溶解度 | DMF: 25 mg/mL,DMSO: 20 mg/mL,Ethanol: 2 mg/mL,PBS (pH 7.2): 3 mg/mL |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
Taurocholic acid-d4 (TCA-d4) is intended for use as an internal standard for the quantification of TCA by GC- or LC-MS. TCA is a taurine-conjugated form of the primary bile acid cholic acid .1 Serum levels of TCA are decreased in patients with Crohn's disease and those with ulcerative colitis with no extraintestinal manifestations, but are increased in patients with ulcerative colitis accompanied by hepatobiliary disease.2
1.Lefebvre, P., Cariou, B., Lien, F., et al.Role of bile acids and bile acid receptors in metabolic regulationPhysiol. Rev.89(1)147-191(2009) 2.Gnewuch, C., Liebisch, G., Langmann, T., et al.Serum bile acid profiling reflects enterohepatic detoxification state and intestinal barrier function in inflammatory bowel diseaseWorld J. Gastroenterol.15(25)3134-3141(2009)
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