Taurodeoxycholic Acid (sodium salt hydrate)CS-01Y69066_上海莼试生物技术有限公司

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化学性质：

规格	1 g 5 g 25 g
CAS	207737-97-1
别名	N/A
化学名	N/A
分子式	C26H44NO6S·Na [XH2O]
分子量	521.7
溶解度	DMF: 25 mg/ml,DMSO: 20 mg/ml,Ethanol: 2 mg/ml,PBS (pH 7.2): 3 mg/ml
储存条件	-20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

产品描述：

Taurodeoxycholic acid is a taurine-conjugated form of the secondary bile acid deoxycholic acid .1 Taurodeoxycholic acid stimulates chloride ion secretion through calcium-activated chloride ion channels and cystic fibrosis transmembrane conductance regulator (CFTR) in Calu-3 airway epithelial cell monolayers when applied basolaterally.2 Serum levels of taurodeoxycholic acid increase approximately 5-fold within two hours during an oral lipid tolerance test in humans.1

1.Schmid, A., Neumann, H., Karrasch, T., et al.Bile acid metabolome after an oral lipid tolerance test by liquid chromatography-tandem mass spectrometry (LC-MS/MS)PLoS One11(2)e0148869(2016) 2.Hendrick, S.M., Mroz, M.S., Greene, C.M., et al.Bile acids stimulate chloride secretion through CFTR and calcium-activated Cl- channels in Calu-3 airway epithelial cellsAm. J. Physiol. Lung. Cell. Mol. Physiol.307(5)L407-L418(2014)

特别提醒：

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。

标签：Taurodeoxycholic Acid (sodium salt hydrate)

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