化学性质:
规格 | 10mM (in 1mL EtOH) 50mg |
CAS | 29925-17-5 |
别名 | 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone |
化学名 | (S)-4-(3-butoxy-4-methoxybenzyl)imidazolidin-2-one |
分子式 | C15H22N2O3 |
分子量 | 278.35 |
溶解度 | 25 mg/mL in DMSO, 30 mg/mL in DMF, 25 mg/mL in Ethanol |
储存条件 | Store at- 20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
Ro 20-1724 is a cell-permeable, cAMP-specific phosphodiesterase type IV (PDE4) inhibitor (IC50 = 2 μM).[1],[2] It weakly inhibits PDE3 with a Ki value greater than 25 μM.1 Ro 20-1724 inhibits the release of cytokines and other inflammatory signals as well as prevents the development of reactive oxygen species.[3] It is often used to study cAMP-related functions in vascular cells.[4]
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