Rosuvastatin lactoneCS-01Y68695_上海莼试生物技术有限公司

产品详情

一、概述：

化学性质：

规格	5 mg 10 mg 25 mg 50 mg
CAS	503610-43-3
别名	N/A
化学名	N/A
分子式	C22H26FN3O5S
分子量	463.5
溶解度	DMF: 30 mg/ml,DMSO: 15 mg/ml,Ethanol: slightly soluble
储存条件	-20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

产品描述：

Rosuvastatin lactone is the lactone form of the HMG-CoA reductase inhibitor rosuvastatin .1 It is found in vivo following rosuvastatin administration.2 Rosuvastatin lactone is an inhibitor of the cytochrome P450 (CYP) isoforms CYP2C9.1 and CYP2C9.3 (IC50s = 8.52 and 4.1 μM, respectively).1

1.Shiozawa, A., Yamaori, S., Kamijo, S., et al.Effects of acid and lactone forms of statins on S-warfarin 7-hydroxylation catalyzed by human liver microsomes and recombinant CYP2C9 variants (CYP2C9.1 and CYP2C9.3)Drug Metab. Pharmacokinet.36100364(2021) 2.Martin, P.D., Warwick, M.J., Dane, A.L., et al.Metabolism, excretion, and pharmacokinetics of rosuvastatin in healthy adult male volunteersClin. Ther.25(11)2822-2835(2003)

特别提醒：

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。

标签：Rosuvastatin lactone

热卖产品最新促销最新推荐

抑制剂 > 新陈代谢类 > Rosuvastatin lactone

产品简介

产品详情

一、概述：

联系我们