化学性质:
规格 | 5mg 10mg 25mg 50mg |
CAS | 1010396-29-8 |
别名 | N/A |
化学名 | N/A |
分子式 | C18H13ClF4N2O3 |
分子量 | 416.8 |
溶解度 | DMF: 20 mg/ml,DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml,DMSO: 14 mg/ml,Ethanol: 10 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
S-23 is a selective androgen receptor modulator (SARM). It binds to the AR (Ki = 1.7 nM) and induces AR-mediated transcriptional activation in CV-1 cells expressing the human receptor when used at a concentration of 10 nM. S-23 increases prostate, seminal vesicle, and levator ani muscle weights in castrated rats. It decreases testicular sperm concentration without reducing mounting behavior or the number of intromissions in intact rats when administered in combination with estradiol benzoate . S-23 (3 mg/kg) also increases preference for sexually active intact males when administered to ovariectomized female rats.
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标签:S-23
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