上海莼试生物技术有限公司
上海莼试生物技术有限公司
化学性质：
| 规格 | 1mg 5mg 10mg 25mg |
| CAS | 18 |
| 别名 | N/A |
| 化学名 | (R)-methyl ((5E,8E,11E,14E)-icosa-5,8,11,14-tetraen-1-yl)phosphonofluoridate |
| 分子式 | C21H36FO2P |
| 分子量 | 370.49 |
| 溶解度 | 3mg/mL in ethanol, or DMSO or DMF |
| 储存条件 | Desiccate at -80°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述：
Methyl arachidonyl fluorophosphonate (MAFP) is a selective, active-site directed, irreversible inhibitor of cPLA2 and iPLA2.[1],[2],[3] It inhibits A23187-induced arachidonic acid release from human platelets with an IC50 value of 0.6 μM.1 The IC50 value for inhibition of iPLA2 from P388D1 cells is 0.5 μM.2 MAFP is a potent inhibitor of fatty acid amide hydrolase, exhibiting an IC50 value of 2.5 nM. MAFP also binds to the CB1 receptor in rat brain membrane preparations. The IC50 values for MAFP and arachidonyl ethanolamide in this assay are 20 and 40 nM, respectively.[4]
特别提醒：
1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
标签：MAFP
联系人：高小姐
手 机：13585831301
Q Q：3004967995
座 机：021-59541103
传 真：021-60443211
地 址：上海嘉定区嘉罗公路1661
