化学性质:
规格 | 5mg 10mg 50mg 100mg |
CAS | 16496-99-4 |
别名 | N/A |
化学名 | 1R,2,3,4,4aS,9,10,10aR-octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenemethanamine, monohydrochloride |
分子式 | C20H31N.HCl |
分子量 | 321.9 |
溶解度 | DMF: 20 mg/ml,DMSO: 25 mg/ml,DMSO:PBS (pH 7.2) (1:2): .15 mg/ml,Ethanol: 20 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
Leelamine is a diterpene molecule whose name derives from the Sanskrit word leela which means “play'- It has weak affinity for the human central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors, exhibiting 20% displacement of [3H]-CP55940 at a concentration of 10 uM. Leelamine inhibits pyruvate dehydrogenase kinase (PDK) with an IC50 of 9.5 uM. Derivatives of leelamine exhibit anti-inflammatory activity and show moderate inhibition of phospholipase A2 activity from a variety of sources.
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