上海莼试生物技术有限公司
上海莼试生物技术有限公司
化学性质：
| 规格 | 10mM (in 1mL DMSO) 10mg 100mg |
| CAS | 330808-88-3 |
| 别名 | N/A |
| 化学名 | 2-[2-ethoxy-5-(4-ethylpiperazin-1-yl)sulfonylphenyl]-5-methyl-7-propyl-1H-imidazo[5,1-f][1,2,4]triazin-4-one |
| 分子式 | C23H32N6O4S.HCl.3H2O |
| 分子量 | 579.11 |
| 溶解度 | ≥ 13.3 mg/mL in DMSO, ≥ 3.42 mg/mL in EtOH with ultrasonic and warming, ≥ 95 mg/mL in H2O |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述：
Vardenafil is a potent and selective inhibitor of phosphodiesterase type5 (PDE5) with the IC50 value of 0.7 nM in enzymatic assay in vitro [1]. Vardenafil HCl Trihydrate is a salt form of vardenafil. [1]
Vardenafil has shown a greater selective inhibition towards PDE5 than PDEs from bovine, with the IC50 values of 180nM,>10000nM, 2500nM, 4000nM and 11nM for PDE1, PDE2, PDE3, PDE4 and PDE6, respectively. Besides, Vardenafil has been reported to significantly enhance the SNP-induced, ACh-induced and transmural electrical stimulation-induced relaxation of human trabecular smooth muscle. Vardenafil has been revealed to increase the amount of cGMP in human corpus cavernosum. Apart from these, Vardenafil has also enhanced the length of penile in the conscious rabbit [1].
特别提醒：
1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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