化学性质:
规格 | 250mg 500mg |
CAS | 2166616-75-5 |
别名 | N/A |
化学名 | N/A |
分子式 | C23H25FN2O3 |
分子量 | 396.45 |
溶解度 | DMSO: 300 mg/mL (756.72 mM) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
LY-3381916 is a potent, selective and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1[1].
LY-3381916 (up to 100 μM) shows no obvious agonism of aryl hydrocarbon receptor (AHR)[1].
[1]. Frank C. Dorsey, et al. Abstract 5245: Identification and characterization of the IDO1 inhibitor LY3381916. Cancer Research. 2018, 78(13).
特别提醒:
1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2. 为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
标签:LY-3381916
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