化学性质:
规格 | 25 mg |
CAS | 219315-22-7 |
别名 | N/A |
化学名 | N/A |
分子式 | C14H10Cl4N2O |
分子量 | 364.05 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
Mitochondrial fusion promoter. Protects cells from mitochondrial fragmentation-associated cell death. Induces mitochondrial fusion in effector T cells imposing a memory T cell morphology. Improves cellular respiration and potentiates glucose-stimulated insulin-secretion in cholesterol-exposed pancreatic β cells.
Asalla et al (2016) Restoring mitochondrial function: a small molecule-mediated approach to enhance glucose stimulated insulin secretion in cholesterol accumulated pancreatic beta cells. Sci.Rep. 10 27513 PMID:27282931 |Wang et al (2012) A small molecule promotes mitochondrial fusion in mammalian cells. Angew.Chem.Int.Ed.Engl. 51 9302 PMID:22907892 |Buck et al (2016) Mitochondrial dynamics controls T cell fate through metabolic programming. Cell 166 63 PMID:27293185
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