15-deoxy-δ12,14-Prostaglandin J2-d4CS-01Y68253_上海莼试生物技术有限公司

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一、概述：

化学性质：

规格	25 μg 50 μg 100 μg
CAS	1542166-82-4
别名	N/A
化学名	N/A
分子式	C20H24D4O3
分子量	320.5
溶解度	DMF: >100 mg/ml (from PGD2),DMSO: >50 mg/ml (from PGD2),Ethanol: >75 mg/ml (from PGD2),PBS pH 7.2: >2.7 mg/ml (from 15-deoxy-d12,
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

产品描述：

15-deoxy-δ12,14-PGJ2-d4 contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of 15-deoxy-δ12,14-PGJ2 by GC- or LC-mass spectrometry. 15-deoxy-δ12,14-Prostaglandin J2 (15-deoxy-δ12,14-PGJ2) is a metabolite of PGJ2. 15-deoxy-δ12,14-PGJ2 is formed from PGD2 by the elimination of two molecules of water. It binds selectively to PPARγ with an EC50 of 2 μM in a murine chimera system.1,2 15-deoxy-δ12,14-PGJ2 is more potent than PGD2, δ12-PGJ2, and PGJ2 in stimulating lipogenesis in C3H10T1/2 cells. The EC50 for induction of adipocyte differentiation in cultured fibroblasts is 7 μM.

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标签：15-deoxy-δ12 14-Prostaglandin J2-d4

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