15-deoxy-Δ-12,14-Prostaglandin J2CS-01Y68171_上海莼试生物技术有限公司

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一、概述：

化学性质：

规格	100ug 500ug 1mg 5mg
CAS	87893-55-8
别名	15-deoxy-Δ12,14-PGJ2
化学名	(E)-7-((S,Z)-5-((E)-oct-2-en-1-ylidene)-4-oxocyclopent-2-en-1-yl)hept-5-enoic acid
分子式	C20H28O3
分子量	316.44
溶解度	DMF: >100 mg/ml (from PGD2), DMSO: >20 mg/ml, Ethanol: >75 mg/ml (from PGD2)
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

产品描述：

15-deoxy-Δ12,14-Prostaglandin J2 (15-deoxy-Δ12,14-PGJ2) is formed from PGD2 by the elimination of two molecules of water. It binds selectively to PPARγ with an EC50 value of 2 μM in a murine chimera system.[1],[2] 15-deoxy-Δ12,14-PGJ2 is more potent than PGD2, Δ12-PGJ2, and PGJ2 in stimulating lipogenesis in C3H10T1/2 cells. The EC50 for induction of adipocyte differentiation in cultured fibroblasts is 7 μM.[1]

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标签：15-deoxy-Δ-12 14-Prostaglandin J2

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