化学性质:
规格 | 1mg 5mg 10mg 25mg |
CAS | 100991-92-2 |
别名 | DAB |
化学名 | 2R-(hydroxymethyl)-3R,4R-pyrrolidinediol, monohydrochloride |
分子式 | C5H11NO3?HCl |
分子量 | 169.6 |
溶解度 | 10 mg/ml in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
1,4-dideoxy-1,4-imino-D-Arabinitol (DAB) is an inhibitor of glycogen phosphorylase, a key enzyme in glycogenolysis. It inhibits glycogenolysis in isolated liver cells (IC50 = 1.0 µM) and in homogenates of cerebral cortex and cerebellum (IC50s = 463 and 383 nM, respectively).[1][2][3] DAB is used to inhibit glycogenolysis, in liver and in brain, in various animal models.[4][5][6]
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