化学性质:
规格 | 25μg 50μg 100μg 500μg |
CAS | 895127-64-7 |
别名 | N/A |
化学名 | N/A |
分子式 | C22H32O3 |
分子量 | 344.5 |
溶解度 | DMF: 25 mg/mL,DMSO: 20 mg/mL,Ethanol: 50 mg/mL,Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/mL |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers. (±)13(14)-EpDPA is a docosahexaenoic acid epoxygenase metabolite, derived via epoxidation of the 13,14-double bond of DHA. It has been detected in rat brain and spinal cord and is a preferred substrate for soluble epoxide hydrolase with a Km value of 3.2 μM. (±)13(14)-EpDPA demonstrates antihyperalgesic activity in inflammatory and neuropathic pain models. (±)13(14)-EpDPA and other epoxy metabolites of DHA are also reported to potently inhibit angiogenesis and tumor growth in in vitro assays.
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