化学性质:
规格 | 5mg 10mg 50mg 100mg 200mg 500mg |
CAS | 2156655-68-2 |
别名 | N/A |
化学名 | N/A |
分子式 | C22H21N9O2 |
分子量 | 443.46 |
溶解度 | DMSO: 250 mg/mL (563.75 mM) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
Autotaxin-IN-3 is a Autotaxin(ATX) inhibitor with an IC50 of 2.4 nM, compound 33, sourced from patent WO2018212534A1[1].
Autotaxin is an enzyme which is responsible for the increase in lysophosphatidic acid in ascites and plasma, and it is a secretory enzyme important for converting lysophosphatidylchloine (LPC) into lysophosphatidic acid (LPA) as a bioactive signaling molecule[1].
[1]. LEE, Dae Yon, et al. NOVEL COMPOUNDS AS AUTOTAXIN INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME. Patent O2018212534A1
特别提醒:
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2. 为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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