化学性质:
规格 | 2mg 5mg 10mg 25mg 50mg |
CAS | 111 |
别名 | N/A |
化学名 | N/A |
分子式 | C24H29ClO7 |
分子量 | 464.94 |
溶解度 | DMSO : ≥ 100 mg/mL (215.08 mM) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
Bexagliflozin is a potent and selective SGLT2 inhibitor with IC50 value of 5.6 uM /2 nM in SGLT1 /SGLT2 respectively.target: SGLT2IC50: 5.6 uM (SGLT1)/ 2 nM (SGLT2)1) In normal rats and dogs a saturable urinary glucose excretion was produced with an ED50 of 0.38 and 0.09 mg/kg, respectively.2) EGT1442 significantly prolonged the median survival of SHRSP rats.3) EGT1442 dose-dependently reduced HbA1c and blood glucose concentration without affecting body mass or insulin level.
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