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抑制剂 > 新陈代谢类 > BI-409306
产品名称:
BI-409306
型号:
CS-01Y68057
生产地址
进口、国产
产品价格
电议
产品简介
质量保证、价格优惠
产品详情

一、概述:

化学性质:                                                                                                             

规格

5mg 10mg 25mg 50mg 100mg

CAS

1189767-28-9

别名

N/A

化学名

N/A

分子式

C16H17N5O2

分子量

311.34

溶解度

DMSO : 75 mg/mL (240.89 mM)

储存条件

Store at -20°C

General tips

For obtaining a higher solubility , please warm the tube at 37 and shake it in the ultrasonic bath for a while.

Shipping Condition

Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

 

产品描述:                                                                                                            

BI-409306 is a potent and selective PDE9A inhibitor, with an IC50 of 52 nM, and shows weak activity against other PDEs, such as PDE1A (IC50, 1.4 uM), PDE1C (IC50, 1.0 uM), PDE2A, PDE3A, PDE4B, PDE5A, PDE6AB, PDE7A, and PDE10A (IC50 all > 10 uM); BI-409306 can be used in the research of memory enhancement in CNS disorders.

BI-409306 is a potent and selective PDE9A inhibitor, with an IC50 of 52 nM, and shows weak activity against other PDEs, such as PDE1A (IC50, 1.4 uM), PDE1C (IC50, 1.0 uM), PDE2A, PDE3A, PDE4B, PDE5A, PDE6AB, PDE7A, and PDE10A (IC50 all > 10 uM), and has no obvious effect on 95 non-PDE targets at 10 uM. BI-409306 enhances long-term potentiation (LTP) in rat hippocampal slices[1].

特别提醒:                                                                                                              

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。

2. 为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。

标签:BI-409306 

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