化学性质:
规格 | 5mg 10mg 25mg 50mg |
CAS | 88070-98-8 |
别名 |
|
化学名 | 6E-(bromomethylene)tetrahydro-3-(1-naphthalenyl)-2H-pyran-2-one |
分子式 | C16H13BrO2 |
分子量 | 317.2 |
溶解度 | ≤2mg/ml in ethanol;25mg/ml in DMSO;50mg/ml in dimethyl formamide |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
Bromoenol lactone is a potent and irreversible inhibitor of myocardial cytosolic calcium-independent phospholipase A2 (iPLA2) [1].
The iPLA2 has been involved in stimulus-induced arachidonic acid release and lysophospholipid generation. The catalytic action of iPLA2 is responsible for phospholipid remodeling as a housekeeping function. Arachidonic acid and lysophospholipid generated by iPLA2 act as a signaling molecule in cellular functions, including eicosanoid production, glucose-induced insulin secretion, Fas-induced apoptosis, cellular proliferation, membrane traffic in fusion, contribution to myocardial ischemia, and others [2].
特别提醒:
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