Bay 60-7550CS-01Y67980_上海莼试生物技术有限公司

产品详情

一、概述：

化学性质：

规格	10 mM * 1 mL in DMSO 5mg 10mg 100mg
CAS	439083-90-6
别名	BAY 607550
化学名	N/A
分子式
分子量	476.57
溶解度	Acetone: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: 10 mg/ml
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

产品描述：

Bay 60-7550 is a potent and selective PDE2 inhibitor with a Ki of 3.8 nM.

Bay 60-7550 (1 μM) increases cGMP in the neuronal cultures compared with control [F(6,14)=12.97, p<0.05 for Bay 60-7550]. Bay 60-7550 in the presence of NMDA (30 μM) results in further increases in cGMP compared with NMDA alone. The NMDA receptor antagonist MK-801 (10 μM) blocks both Bay 60-7550+NMDA-induced elevation in cGMP in neuronal cultures[1]. Compared with untreated control cells, proliferation of PASMCs from IPAH patients is significantly reduced by BAY 60-7550 (1 μM)[2].

特别提醒：

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。

标签：Bay 60-7550

热卖产品最新促销最新推荐

抑制剂 > 新陈代谢类 > Bay 60-7550

产品简介

产品详情

一、概述：

联系我们