7-EthoxycoumarinCS-01Y67950_上海莼试生物技术有限公司

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一、概述：

化学性质：

规格	100 mg 250 mg 500 mg 1 g
CAS	31005-02-4
别名	N/A
化学名	N/A
分子式	C11H10O3
分子量	190.2
溶解度	DMF: 30 mg/ml,DMF:PBS (pH 7.2) (1:1): 0.50 mg/ml,DMSO: 15 mg/ml
储存条件	-20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

产品描述：

7-Ethoxycoumarin is a substrate for cytochrome P450 (CYP).1 It undergoes O-deethylation by various CYP isoforms, including CYP1A1, -1A2, and -2B in mice and CYP2E1 in humans. 7-Ethoxycoumarin has been used in the functional characterization of CYPs in cats, rats, and isolated human cornea.2,3,4

1.Okamatsu, G., Komatsu, T., Kubota, A., et al.Identification and functional characterization of novel feline cytochrome P450 2AXenobiotica45(6)503-510(2015) 2.Kajbaf, M., Ricci, R., Zambon, S., et al.Contribution of rat intestinal metabolism to the xenobiotics clearanceEur. J. Drug Metab. Pharmacokinet.38(1)33-41(2013) 3.K?lln, C., and Reichl, S.Cytochrome P450 activity in ex vivo cornea models and a human cornea constructJ. Pharm. Sci.105(7)2204-2212(2016)

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1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。

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标签：7-Ethoxycoumarin

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