3,5-Diiodo-L-thyronineCS-01Y67933_上海莼试生物技术有限公司

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一、概述：

化学性质：

规格	500 mg 1 g 5 g 10 g
CAS	1041-01-6
别名	N/A
化学名	N/A
分子式	C15H13I2NO4
分子量	525.1
溶解度	DMF: 1 mg/ml,DMSO: insol,Ethanol: insol,PBS (pH 7.2): insol
储存条件	-20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

产品描述：

3,5-Diiodo-L-thyronine (3,5-T2) is a thyroid hormone metabolite.1 It binds to thyroid hormone receptor α1 (TRα1), TRβ1, and TRβ2 (EC50s = 0.8, 0.79, and 0.1 μM, respectively, in cell-free assays).2 3,5-T2 (1 pM) stimulates oxygen consumption in perfused livers isolated from rats with hypothyroidism induced by sodium iodide.3 It reduces subcutaneous and epididymal fat mass, as well as decreases serum leptin and cholesterol levels, without affecting body weight in high-fat diet-induced obese mice when administered at a dose of 2.5 μg/g per day.1

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标签：3 5-Diiodo-L-thyronine

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