化学性质:
规格 | 1mg 5mg 10mg 25mg |
CAS | 7 |
别名 | (S)-5-Ethyl-3-methyl-5-phenylhydantoin |
化学名 | (5S)-5-ethyl-3-methyl-5-phenyl-2,4-imidazolidinedione |
分子式 | C12H14N2O2 |
分子量 | 218.3 |
溶解度 | 15mg/ml in ethanol;25mg/ml in DMSO;25mg/ml in dimethyl formamide |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
(S)-Mephenytoin is a substrate of the cytochrome P450 (CYP) isoform CYP2C19, also known as mephenytoin 4-hydroxylase.[1] CYP2C19 metabolizes a variety of therapeutic agents, including omeprazole, proguanil, diazepam, propranolol, citalopram, imipramine, and certain barbiturates.[2] Genetic defects in CYP2C19 result in poor metabolism of these compounds, and (S)-mephenytoin can be used to screen for such mutations by assaying its metabolites in urine.[2],[3],[4] (S)-Mephenytoin has anticonvulsant activities.[5]
特别提醒:
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