上海莼试生物技术有限公司
上海莼试生物技术有限公司
化学性质：
| 规格 | 10mg 25mg 50mg 100mg |
| CAS | 71140-51-7 |
| 别名 | (–)-Mephenytoin |
| 化学名 | (5R)-5-ethyl-3-methyl-5-phenyl-2,4-imidazolidinedione |
| 分子式 | C12H14N2O2 |
| 分子量 | 218.3 |
| 溶解度 | 15mg/mL in ethanol, 25mg/mL in DMSO, or in DMF |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述：
(R)-Mephenytoin is the (R) enantiomer of the anticonvulsant mephenytoin.[1] (R)-Mephenytoin can be demethylated by the cytochrome P450 (CYP) isoform CYP2C9 to form the active metabolite 5-ethyl-5-phenylhydantoin (nirvanol). [2][3]The ratio of (S)-mephenytoin to (R)-mephenytoin in urine following administration of the racemic mixture has been used to detect polymorphisms in drug metabolism by CYP2C19, as only (S)-mephenytoin is a substrate of CYP2C19.[4][5][2]
特别提醒：
1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
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