化学性质:
规格 | 100mg 250mg 500mg |
CAS | 2093317-51-0 |
别名 | N/A |
化学名 | N/A |
分子式 | C18H17FN2S |
分子量 | 312.4 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
CYP17-IN-1 (compound 9c) is a potent and orally active CYP17 inhibitor against rat and human CYP17 with IC50s of 15.8 and 20.1 nM[1]. IC50: 15.8 nM (Rat CYP17), 20.1 nM (Human CYP17)[1]
CYP17-IN-1 (compound 9c) exhibits an IC50 value of 8.5 µM against CYP3A4[1].
CYP17-IN-1 (compound 9c) reduces plasma testosterone level in a dose-dependent manner in Sprague-Dawley rats[1].
特别提醒:
1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2. 为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
标签:CYP17-IN-1
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