化学性质:
规格 | 25μg 50μg 100μg |
CAS | 115461-39-7 |
别名 | N/A |
化学名 | N/A |
分子式 | C20H32O3 |
分子量 | 320.5 |
溶解度 | DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 50 mg/ml,PBS (pH 7.2): 0.5 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
19-HETE is one of the major cytochrome P450 (CYP450) metabolites of arachidonic acid that is released from the kidney in response to angiotensin II. When formed by the CYP2E1 isoform, 19-HETE is composed of 70% and 30% of the (S) and (R) stereoisomers, respectively. Both 19(S)- and 19(R)-HETE are potent vasodilators of renal preglomerular vessels. However, 19(R)-HETE at 1 μM completely blocks 20-HETE-induced vasoconstriction of renal arterioles, whereas 19(S)-HETE remains inactive.
特别提醒:
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标签:19(R)-HETE
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