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抑制剂 > 染色质 > β-Glycerophosphate (sodium salt hydrate)
产品名称:
β-Glycerophosphate (sodium salt hydrate)
型号:
CS-01Y67581
生产地址
进口、国产
产品价格
电议
产品简介
质量保证、价格优惠
产品详情

一、概述:

化学性质:                                                                                                             

规格

25g 100g 500g

CAS

13408-09-8

别名

N/A

化学名

2-(dihydrogen phosphate)-1,2,3-propanetriol, disodium salt, pentahydrate

分子式

C3H7O6P ? 2Na [5H2O]

分子量

306.1

溶解度

30.7mg/mL in H2O, 14.3mg/mL in DMSO

储存条件

4°C, protect from light

General tips

For obtaining a higher solubility , please warm the tube at 37 and shake it in the ultrasonic bath for a while.

Shipping Condition

Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

 

产品描述:                                                                                                            

β-Glycerophosphate (sodium salt hydrate) is a potent protein phosphatase inhibitor [1].

Protein phosphatase is an enzyme that removes a phosphate group from the phosphorylated amino acid residue of its target protein. Protein phosphorylation is one of the most common protein posttranslational modifications.

β-Glycerophosphate is a potent protein phosphatase inhibitor that acts as a phosphate group donor in bone cell mineralization studies [1][3]. In MC3T3-E1, ROS 17/2.8, and chick osteoblast-like cells, β-Glycerophosphate did not affect the rate of anaerobic glycolysis, but increased the medium Pi levels, suggesting that β-Glycerophosphate was hydrolyzed by bone cells. The local increase in medium Pi concentration promoted rapid mineral deposition [1]. In human bone marrow stromal cells (HBMSC) and human osteoblasts (HOB), BMP-2 resulted in mineralization of their matrix in the presence of beta-glycerophosphate and ascorbic acid [3]. β-Glycerophosphate (10 mM) also accelerated calcification of cultured vascular smooth muscle cells through an alkaline phosphatase-related mechanism [4].

特别提醒:                                                                                                              

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。

2. 为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。

标签:β-Glycerophosphate (sodium salt hydrate) 

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