化学性质:
规格 | 5mg |
CAS | 3930-19-6 |
别名 | N/A |
化学名 | N/A |
分子式 | C25H22N4O8 |
分子量 | 506.46 |
溶解度 | Chloroform:Methanol (1:1): 2 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
Streptonigrin (Bruneomycin), a natural product produced by Streptomyces flocculus, possesses both anti-tumor and anti-bacterial activity. Streptonigrin acts as a pan-PAD inhibitor with IC50s of 48.3±34.2 μM, 26.1±0.3 μM, 0.43±0.03 μM, and 2.5±0.4 μM for PAD1, PAD2, PAD3, and PAD4, respectively[1].
[1]. Dreyton CJ, et al. Insights into the mechanism of Streptonigrin-induced protein arginine deiminase inactivation. Bioorg Med Chem. 2014 Feb 15;22(4):1362-9.
特别提醒:
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2. 为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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