上海莼试生物技术有限公司
上海莼试生物技术有限公司
化学性质：
| 规格 | 10mM (in 1mL DMSO) 10mg 50mg |
| CAS | 587850-67-7 |
| 别名 |
|
| 化学名 | 4-amino-N-phenethylbenzenesulfonamide |
| 分子式 | C14H16N2O2S |
| 分子量 | 276.35 |
| 溶解度 | ≥ 13.9mg/mL in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述：
C7280948 is a novel PRMT1 inhibitor with IC50 value of 12.75 μM [1].
Protein arginine methyltransferase 1 (PRMT1) is a histone methyltransferase specific for histone H4. PRMT1 catalyzes the transfer of the methyl group from SAM to the guanidine nitrogen atoms of arginine residues to produce monomethyl arginines (MMA) and asymmetric dimethyl arginines (ADMA) [2].
C7280948 is a novel PRMT1 inhibitor. C7280948 interacts with aromatic residues at the hPRMT1 substrate binding pocket (Tyr 147 and Tyr 160) [1]. C7280948 inhibited hPRMT1 with IC50 value of 26.7 μM [3].
特别提醒：
1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
标签：C7280948
联系人：高小姐
手 机：13585831301
Q Q：3004967995
座 机：021-59541103
传 真：021-60443211
地 址：上海嘉定区嘉罗公路1661
