化学性质:
规格 | 10mM (in 1mL DMSO)50mg |
CAS | 1837-91-8 |
别名 |
|
化学名 | 1,2,3,4,5,6-hexabromocyclohexane |
分子式 | C6H6Br6 |
分子量 | 557.54 |
溶解度 | ≥ 8.2mg/mL in DMSO with gentle warming |
储存条件 | Store at RT |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
Potently and directly inhibits JAK2 tyrosine kinase autophosphorylation, specifically inhibiting ligand-dependent JAK2 activation. A 16-hour treatment with 1 μM of compound reduces JAK2 tyrosine autophosphorylation levels to ~ 50% while 50 μM elimates nearly all JAK2 activity. Non-cytotoxic at 100 μM.
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