上海莼试生物技术有限公司
上海莼试生物技术有限公司
化学性质：
| 规格 | 10mM*1mLinDMSO1mg 5mg 10mg 50mg 100mg |
| CAS | 1800340-40-2 |
| 别名 | N/A |
| 化学名 | N/A |
| 分子式 | C30H33N5O2 |
| 分子量 | 495.62 |
| 溶解度 | DMSO : 1 mg/mL (2.02 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述：
BMS-986158 is an inhibitor of the bromodomain and extra-terminal (BET) proteins.
BMS-986158 is an inhibitor of the bromodomain (BRD) and extra-terminal domain (BET) family of proteins, with potential antineoplastic activity. Upon administration, the BET inhibitor BMS-986158 binds to the acetyl-lysine binding site in the BRD of BET proteins, thereby preventing the interaction between BET proteins and acetylated histones. This disrupts chromatin remodeling and prevents the expression of certain growth-promoting genes, resulting in an inhibition of tumor cell growth[2].
[1]. von Schaper E. Roche bets on bromodomains. Nat Biotechnol. 2016 Apr;34(4):361-2. [2]. BET Inhibitor BMS-986158.
特别提醒：
1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
标签：BMS-986158
联系人：高小姐
手 机：13585831301
Q Q：3004967995
座 机：021-59541103
传 真：021-60443211
地 址：上海嘉定区嘉罗公路1661
