GSK121 (trifluoroacetate salt)CS-01Y67019_上海莼试生物技术有限公司

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一、概述：

化学性质：

规格	500μg 1mg 5mg 10mg
CAS	1652591-80-4
别名	N/A
化学名	N/A
分子式	C23H25N5O?CF3COOH
分子量	501.5
溶解度	DMF: 30 mg/ml,DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 10 mg/ml,PBS (pH 7.2): 10 mg/ml
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

产品描述：

Protein arginine deiminase 4 (PAD4) mediates the transformation of protein arginine into citrulline. Citrullination of proteins has normal roles in gene regulation and pathological roles in immunological and inflammatory diseases. GSK121 is the initial compound identified in a screen for PAD4 inhibitors and was optimized to produce the more potent PAD4 inhibitors, GSK484 and GSK199 . GSK121 was shown to inhibit the citrullination of PAD4 target proteins in a functional assay with an IC50 value of 3.2 μM.

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1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。

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标签：GSK121 (trifluoroacetate salt)

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