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抑制剂 > 凋亡抑制类 > Previridicatumtoxin
产品名称:
Previridicatumtoxin
型号:
CS-01Y66680
生产地址
进口、国产
产品价格
电议
产品简介
质量保证、价格优惠
产品详情

一、概述:

化学性质:                                                                                                             

规格

1 mg

CAS

1379585-81-5

别名

N/A

化学名

N/A

分子式

C30H33NO10

分子量

567.6

溶解度

Dichloromethane: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble

储存条件

Store at -20°C

General tips

For obtaining a higher solubility , please warm the tube at 37 and shake it in the ultrasonic bath for a while.

Shipping Condition

Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

 

产品描述:                                                                                                             

Previridicatumtoxin is a fungal metabolite that has been found in P. aethiopicum and has diverse biological activities.1,2 It is an intermediate in the biosynthesis of the mycotoxin viridicatumtoxin . Previridicatumtoxin is active against methicillin-resistant S. aureus (MRSA) and vancomycin-resistant E. faecalis (IC50s = 4.4 and 4.8 μM, respectively), as well as C. albicans and S. cerevisiae (MIC = 32 μg/ml for both).2,1 It is cytotoxic to NCI H460, KB-3-1, and SW620 cancer cells (IC50s = 5.3, 4.1, and 6 μM, respectively).2

1.Chooi, Y.H., Wang, P., Fang, J., et al.Discovery and characterization of a group of fungal polycyclic polyketide prenyltransferasesJ. Am. Chem. Soc.134(22)9428-9437(2012) 2.Shang, Z., Salim, A.A., Khalil, Z., et al.Viridicatumtoxins: Expanding on a rare tetracycline antibiotic scaffoldJ. Org. Chem.80(24)12501-12508(2015)

特别提醒:                                                                                                              

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。

2. 为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。

标签:Previridicatumtoxin 

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