规格 | 10mM (in 1mL DMSO) 20mg 50mg 200mg |
CAS | 284461-73-0 |
别名 | BAY-43-9006,Sorafenib,Nexavar,sorafenibum |
化学名 | 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide |
分子式 | C21H16ClF3N4O3 |
分子量 | 464.82 |
溶解度 | ≥ 23.25mg/mL in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
Sorafenib is an oral multikinase inhibitor with activity against Raf kinase and several receptor tyrosine kinases, including vascular endothelial growth factor receptor 2 (VEGFR2), platelet-derived growth factor receptor (PDGFR), FLT3, Ret, and c-Kit. sorafenib, inhibits tumor growth and disrupts tumor microvasculature through antiproliferative, antiangiogenic, and/or proapoptotic effects. sorafenib blocks Raf kinase signaling, inhibits tumor cell proliferation, and induces apoptosis in vitro. In addition, sorafenib exhibits robust antitumor efficacy.
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2. 为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
标签:Sorafenib
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