规格 | 00μg 1mg 5mg 10mg |
CAS | 25694-72-8 |
别名 | N/A |
化学名 | N/A |
分子式 | C27H30O15 |
分子量 | 594.5 |
溶解度 | DMF: 50 mg/ml,DMSO: 50 mg/ml |
储存条件 | 4°C, protect from light |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
Lonicerin is a flavonoid that has been found in L. japonica and has diverse biological activities, including antioxidant, anti-inflammatory, and neuroprotective properties. Lonicerin inhibits xanthine oxidase (IC50 = 37.4 μg/ml) and scavenges 2,2-diphenyl-1-picrylhydrazyl , hydroxyl, and superoxide radicals (IC50s = 9.2, 236.8, and 143.9 μg/ml, respectively). It reduces paw edema in a mouse model of C. albicans cell wall- and complete Freund's adjuvant-induced arthritis when administered at doses of 1 and 2 mg/kg three times every other day. It also decreases nitric oxide (NO) production and T cell proliferation in vitro when used at concentrations of 20 and 40 μg/ml, respectively. Lonicerin is neuroprotective against glutamate-induced neurotoxicity in rat primary cortical neurons.
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标签:Lonicerin
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