SterigmatocystinCS-01Y66107_上海莼试生物技术有限公司

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一、概述：

化学性质：

规格	500μg 1mg 10mg
CAS	10048-13-2
别名	N/A
化学名	N/A
分子式	C18H12O6
分子量	324.3
溶解度	Acetone: 5 mg/ml
储存条件	4°C, protect from light
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

产品描述：

Sterigmatocystine is a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versicolor[1][2]. Sterigmatocystine, a inhibitor of G1 Phase and DNA synthesis, is used to inhibit p21 activity. Sterigmatocystine has teratogenic, and carcinogenic effects in animals[3].

Sterigmatocystine-induced DNA damage activates the ATM/53-dependent signaling pathway, which contributes to the induction of G2 arrest in GES-1 cells[4].

Sterigmatocystine (ip; 3 mg/kg once daily for 14 days) inhibits p21WAF1/CIP1[3].

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标签：Sterigmatocystin

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抑制剂 > 凋亡抑制类 > Sterigmatocystin

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