Prostaglandin D2 EthanolamideCS-01Y66060_上海莼试生物技术有限公司

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一、概述：

化学性质：

规格	500μg 1mg 5mg
CAS	398138-28-8
别名	N/A
化学名	N/A
分子式	C22H37NO5
分子量	395.5
溶解度	DMF: 8.3 mg/ml,DMSO: 8.3 mg/ml,Ethanol: 12.5 mg/ml,PBS (7.2): 2.5 mg/ml
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

产品描述：

Prostaglandin D2 ethanolamide (PGD2-EA) is a bioactive lipid produced by the sequential metabolism of anandamide (arachidonoyl ethanolamide) by cyclooxygenase (COX) enzymes, in particular by COX-2, and PGD synthase. The biosynthesis of PGD2-EA from anandamide can also be increased when anandamide metabolism is diminished by deletion of fatty acid amide hydrolase. PGD2-EA is inactive against recombinant prostanoid receptors, including the D prostanoid receptor. It increases the frequency of miniature inhibitory postsynaptic currents in primary cultured hippocampal neurons, an effect which is the opposite of that induced by anandamide.. PGD2-EA also induces apoptosis in colorectal carcinoma cell lines

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标签：Prostaglandin D2 Ethanolamide

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