上海莼试生物技术有限公司
上海莼试生物技术有限公司
| 规格 | 500μg 2.5mg |
| CAS | |
| 别名 | N/A |
| 化学名 | 4-formyl-3-hydroxy-8-methoxy-1,9-dimethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepin-6-carboxylic acid |
| 分子式 | C18H14O8 |
| 分子量 | 358.3 |
| 溶解度 | DMSO: Soluble,Ethanol: Soluble |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述：
Psoromic acid is an inhibitor of Rab geranylgeranyl transferase (IC50 = 1.3 uM) and P. falciparum fatty acid synthesis (FAS) II. It shows cytotoxic effects on primary rat cerebral cortex and human cancer U87MG cell lines in vitro (IC50s = 79.40 and 56.22 mg/L, respectively). It also is cytotoxic against human KB cancer cells (IC50 = 31.6 uM). It shows moderate activity against liver stage P. beghei (IC50 = 31.6 uM) and drug-resistant blood stage P. falciparum (IC50 = 29.2 uM). The maximum tolerated dose in zebrafish larvae is 15.5 uM.
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