规格 | 500μg 1mg 5mg |
CAS | 35 |
别名 | 5-Phenyl-2-ureidothiophene-3-carboxylic Acid Amide |
化学名 | 2-[(aminocarbonyl)amino]-5-phenyl-3-thiophenecarboxamide |
分子式 | C12H11N3O2S |
分子量 | 261.3 |
溶解度 | 2mg/mL in ethanol, 30mg/mL in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
Inhibitor of NF-κB kinase 2 (IKK2, also known as IKKβ) acts as part of an IKK complex in the canonical NF-κB pathway, phosphorylating inhibitors of NF-κB (IκBs) to initiate signaling. NF-κB signaling can also occur through a non-canonical, IKK/IκB-independent pathway. IKK2 Inhibitor VI is a potent, cell-permeable, reversible inhibitor of IKK2 (IC50 = 13 nM). [1] It is used to evaluate the role of the canonical, IκB-dependent NF-κB signaling pathway in cellular responses.[2][3]
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