Incensole acetate is a main constituent of Boswellia carterii resin, has neuroprotective effects against neuronal damage in traumatic and ischemic head injury. Incensole acetate reduces Aβ25-35-triggered apoptosis in hOBNSCs[1].

Incensole acetate (100 μM; pre-treatment 4 hours) significantly ameliorates Aβ 25-35-induced cell death, a 48-52% decrease in cell viability at Aβ25-35 is restored to 85-89% upon pre-treatment with IA[1].Incensole acetate (5-100 μM) pretreatment reverses increase in the mRNA and protein level of Bax, caspase 8, cyto c and decrease in the mRNA and protein level of Bcl2 induced by Aβ 25-35 in hOBNSCs[1]. Cell Viability Assay[1] Cell Line: Human olfactory bulb neural stem cells

[1]. El-Magd MA, et al. Incensole acetate prevents beta-amyloid-induced neurotoxicity in human olfactory bulb neural stem cells. Biomed Pharmacother. 2018 Sep;105:813-823.