规格 | 10mM*1mLinDMSO 1g |
CAS | 67-45-8 |
别名 | N/A |
化学名 | N/A |
分子式 | C8H7N3O5 |
分子量 | 225.16 |
溶解度 | DMSO : 10 mg/mL (44.41 mM);H2O : < 0.1 mg/mL (insoluble) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
Furazolidone is a nitrofuran derivative with antiprotozoal and antibacterial activity, inhibits AML1-ETO transformed cells with IC50 value of 12.7 μM.Target: Antibacterial Furazolidone is a novel therapeutic strategy in AML patients. Furazolidone can Inhibit the bone-marrow transformation mediated by a series of leukemia fusion proteins. Furazolidone significantly inhibits proliferation of AML cell lines. Furazolidone induces apoptosis of the AML leukemic cells treatment with Furazolidone induces differentiation of AML cell lines.
[1]. Jiang X, et al. A novel application of furazolidone: anti-leukemic activity in acute myeloid leukemia. PLoS One. 2013 Aug 9;8(8):e72335.
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标签:Furazolidone
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