上海莼试生物技术有限公司
上海莼试生物技术有限公司
| 规格 | 25ug 50ug 100ug 500ug |
| CAS | 126643-37-6 |
| 别名 | N/A |
| 化学名 | (5S,6S,8S)-methyl 6-methoxy-5,14-dimethyl-13-oxo-6,7,8,13,14,15-hexahydro-5H-16-oxa-4b,8a,14-triaza-5,8-methanodibenzo[b,h]cycloocta[jkl]cyclopenta[e]-as-indacene-6-carboxylate |
| 分子式 | C29H25N3O5 |
| 分子量 | 495.53 |
| 溶解度 | 1mg/mL in ethyl acetate or 20mg/mL in DMSO |
| 储存条件 | Desiccate at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述：
The activity of cGMP-dependent protein kinase (PKG) is controlled by factors that elevate cellular cGMP, like nitric oxide (NO), and by those that reduce cGMP levels, like certain phosphodiesterases. KT 5823 is a potent, selective inhibitor of cGMP-dependent protein kinase (PKG) (in vitro IC50 = 234 nM).1 KT 5823 is cell-permeable and is often used in intact cells to assess the role of PKG in signaling, although there are cases where it poorly inhibits PKG in cells.[2] KT 5823 is a weak inhibitor of PKC (Ki = 4 µM) and PKA (Ki >10 µM).[1]
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2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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