化学性质:
规格 | 5 mg 10 mg 25 mg 50 mg 100 mg |
CAS | 2416095-00-4 |
别名 | N/A |
化学名 | N/A |
分子式 | C12H13Cl2NO6S2 |
分子量 | 402.27 |
溶解度 | DMSO: 200 mg/mL (497.18 mM) |
储存条件 | 4°C, stored under nitrogen |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
CBR-470-2 (1-10 μM; 24 h) increases transcript levels of the NRF2-responsive genes NQO1 and HMOX1 in epidermal keratinocytes and dermal fibroblasts[1].
CBR-470-2 (50 mg/kg; p.o. twice daily for 10 d) induces activation of NRF2 signaling in vivo[1]. Animal Model: Balb/C mice (5-week old) are exposed to UVB[1]
[1]. Bollong MJ, et, al. A metabolite-derived protein modification integrates glycolysis with KEAP1-NRF2 signalling. Nature. 2018 Oct;562(7728):600-604.
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标签:CBR-470-2
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