DacarbazineCS-01Y65478_上海莼试生物技术有限公司

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一、概述：

化学性质：

规格	10mM (in 1mL DMSO) 200mg 1g
CAS	4342/3/4
别名
化学名	(5E)-5-(dimethylaminohydrazinylidene)imidazole-4-carboxamide
分子式	C6H10N6O
分子量	182.18
溶解度	≥ 2.3mg/mL in DMSO, ≥ 0.54 mg/mL in H2O, <0.49 mg/mL in EtOH
储存条件	4°C, protect from light
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

产品描述：

Dacarbazine is commonly used as a single agent in the treatment of metastatic melanoma in middle of 2006, and as part of the ABVD chemotherapy regimen to treat Hodgkin lymphoma, and in the MAID regimen for sarcoma.Currently, Dacarbazine combined with Oblimersen for the treatment of malignant melanoma in clinical trials.[3]Dacarbazine is normally administered by injection (a shot) or intravenous infusion (IV) under the immediate supervision of a doctor or nurse.Now in phase III about Melanoma Recurrent 2015 March.

References:1. "Alkylating Agents". US National Library of Medicine. Retrieved 2 August 2014.

2. Wiedemann GJ. et al. "Ifosfamide, carboplatin and etoposide (ICE) combined with 41.8 degrees C whole body hyperthermia in patients with refractory sarcoma". European Journal of Cancer 1996,32A (5): 888–92.

3. MedLine, U.S. National Institutes of Health, National Library of Medicine.

4. CClinicalTrials.gov Identifier:NCT02288897.

特别提醒：

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。

标签：Dacarbazine

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