化学性质:
规格 | 500 μg 1 mg |
CAS | 1537187-53-3 |
别名 | N/A |
化学名 | N/A |
分子式 | C40H49D8N5O7 |
分子量 | 728 |
溶解度 | DMF: 15 mg/ml,DMSO: 15 mg/ml,Ethanol: 1 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
1.Dou, Q.P., and Zonder, J.A.Overview of proteasome inhibitor-based anti-cancer therapies: Perspective on bortezomib and second generation proteasome inhibitors versus future generation inhibitors of ubiquitin-proteasome systemCurr. Cancer Drug Targets14(6)517-536(2014) 2.Zhou, H.J., Aujay, M.A., Bennett, M.K., et al.Design and synthesis of an orally bioavailable and selective peptide epoxyketone proteasome inhibitor (PR-047)J. Med. Chem.52(9)3028-3038(2009) 3.Zhang, W., and Sidhu, S.S.Development of inhibitors in the ubiquitination cascadeFEBS Lett.588(2)356-367(2014) 4.Demo, S.D., Kirk, C.J., Aujay, M.A., et al.Antitumor activity of PR-171, a novel irreversible inhibitor of the proteasomeCancer Res.67(13)6383-6391(2007)
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