上海莼试生物技术有限公司
上海莼试生物技术有限公司
化学性质：
| 规格 | 10mM (in 1mL DMSO) 20mg |
| CAS | 477-90-7 |
| 别名 | |
| 化学名 | (2R,3S,4S,4aR,10bS)-3,4,8,10-tetrahydroxy-2-(hydroxymethyl)-9-methoxy-3,4,4a,10b-tetrahydro-2H-pyrano[3,2-c]isochromen-6-one |
| 分子式 | C14H16O9 |
| 分子量 | 328.27 |
| 溶解度 | ≥ 14.55mg/mL in DMSO |
| 储存条件 |
|
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述：
Bergenin (7.5-30μM; 24 hours) decreases the viability of HeLa cervical cancer cells (IC50=15 μM)[1].Bergenin (7.5-30 μM; 24 hours) induces apoptosis in HeLa cervical cancer cells[1].
Pretreatment with Bergenin (12.5-100 mg/kg; i.p.; once) produces a dose-related inhibition of acetic acid-induced writhing in mice[3].
References:
[1]. Shi X, et al. Anticancer activity of bergenin against cervical cancer cells involves apoptosis, cell cycle arrest, inhibition of cell migration and the STAT3 signalling pathway. Exp Ther Med. 2019 May;17(5):3525-3529.
[2]. Yun J, et al. Bergenin decreases the morphine-induced physical dependence via antioxidative activity in mice. Arch Pharm Res. 2015 Jun;38(6):1248-54.
[3]. de Oliveira CM, et al. Antinociceptive properties of bergenin. J Nat Prod. 2011 Oct 28;74(10):2062-8.
特别提醒：
1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
标签：Bergenin
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