(R)-(+)-Etomoxir sodium saltCS-01Y65199_上海莼试生物技术有限公司

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一、概述：

化学性质：

规格	10mM (in 1mL DMSO) 10mg 50mg 500mg 1g
CAS	828934-41-4
别名	N/A
化学名	sodium (R)-2-(6-(4-chlorophenoxy)hexyl)oxirane-2-carboxylate
分子式	C15H18ClNaO4
分子量	320.74
溶解度	≥ 12mg/mL in DMSO
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

产品描述：

Etomoxir sodium salt ((R)-(+)-Etomoxir sodium salt) is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig.

References:

[1]. Agius L, et al. Differences between human, rat and guinea pig hepatocyte cultures. A comparative study of their rates of beta-oxidation and esterification of palmitate and their sensitivity to R-etomoxir. Biochem Pharmacol. 1991 Oct 9;42(9):1711-5.

[2]. O'Connor RS, et al. The CPT1a inhibitor, etomoxir induces severe oxidative stress at commonly used concentrations. Sci Rep. 2018 Apr 19;8(1):6289.

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标签：(R)-(+)-Etomoxir sodium salt

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