β-Elemonic AcidCS-01Y65105_上海莼试生物技术有限公司

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一、概述：

化学性质：

规格	1mg 5mg 10mg 25mg
CAS	28282-25-9
别名	N/A
化学名	N/A
分子式	C30H46O3
分子量	454.7
溶解度	DMF: 30 mg/ml,DMF:PBS (pH 7.2)(1:3): 0.25 mg/ml,DMSO: 5 mg/ml,Ethanol: 5 mg/ml
储存条件	4°C, protect from light
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

产品描述：

β-Elemonic acid is a triterpene isolated from Boswellia (Burseraceae) that exhibits anticancer activity. It inhibits growth of non-small cell lung cancer (NSCLC) A549 cells (IC50 = 6.92 μM) in vitro. β-Elemonic acid induces apoptosis and cytotoxicity in A549 cells in a dose-dependent manner but has no effect on normal epithelial WI-38 cells. It inhibits phosphorylation of p42/44, MAPK/JNK, and p38 and induces production of reactive oxygen species (ROS) and COX-2 expression in vitro. β-Elemonic acid also inhibits prolyl endopeptidase (IC50 = 39.74 μM) in vitro

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标签：β-Elemonic Acid

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